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AIM: To evaluate the clinical effect of trabeculectomy combined with bio-amnion implantation for patients with refractory glaucoma. METHODS: Totally 62 eyes of 46 glaucoma patients were randomly divided into 2 groups. In group A, 32 eyes underwent trabeculectomy combined with bio-amnion implantation. In group B,30 eyes were as control group. The intraocular pressure (IOP), filtrative bleb, visual acuity and complications were observed. RESULTS: Following-up 12 months, the postoperative conditions were compared with those before the surgery. The IOP of both groups was significantly declined (P < 0.01). The average IOP in group A was about 12.3 (plus or minus) 2.3mmHg, while in group B was about 15.7 (plus or minus) 2.7mmHg. 88% was I and II bleb in group A, 67% was I and II bleb in group B. There was significant difference between two groups (P < 0.05). Postoperative complications: shallow anterior chamber:5 eyes in group A,3 eyes in group B; choroidal detachment:2 eyes in group A ,2 eyes in group B; bleb leaking:1 eye in group B. CONCLUSION: Combined trabeculectomy with bioamnion implantation can increase the success ratio in refractory glaucoma surgery. LA: Chinese
L. Li. Department of Ophthalmology, Daqing People's Hospital, Harbin Medical University, Daqing 163316, Heilongjiang Province, China. lileidq76@yahoo.com.cn
12.8.10 Woundhealing antifibrosis (Part of: 12 Surgical treatment > 12.8 Filtering surgery)