advertisement
Abstract #27602 Published in IGR 12-4
Clinical effect of non-penetrating trabecular surgery with human umbilical vein implant and mitomycin C for treatment of primary open angle glaucoma
Li X; Liu H-N; Gao D-WInternational Journal of Ophthalmology 2010; 10: 1895-1896
AIM: To evaluate the clinical effect of non - penetrating trabecular surgery (NPTS) with human umbilical vein (HUV) implant and mitomycin C (MMC) in patients with primary open angle glaucoma (POAG). METHODS: NPTS with HUV implant and MMC was performed on 42 eyes of 42 patients with POAG. The outcome's evaluation included postoperative intraocular pressure (IOP), number of anti-glaucoma medications, the morphologic characteristics of the filtering blebs and complications. All patients were followed up for 12 months. RESULTS: The postoperative complete success rate was 81% and qualified success rate was 95% at 12 months after surgery respectively; IOP was decreased from (26.1 (plus or minus) 7.7) mmHg to (15.3 (plus or minus) 3.8) mmHg at 12 months (P = 0.00); the number of anti-glaucoma medications was decreased from (3.2 (plus or minus) 0.5) to (0.3 (plus or minus) 0.2) at 12 months (P = 0.00); the morphologic characteristics of the filtering blebs: type I was 26%, type II was 59%, type IV was 14%. Encapsulated bleb was observed in 6 eyes and there was a small amount of hyphema that was absorbed in 3 eyes, but the complications such as flat chamber, hypotony and choroidal effusion were not observed. CONCLUSIONS: NPTS with HUV implant and MMC might improve the clinical outcome of the patients with POAG, such as higher success rates, lower postoperative mean IOP, and less complication rates. LA: Chinese
X. Li. Department of Ophthalmology, Shengjing Hospital, China Medical University, Shenyang 110004, Liaoning Province, China. China.lixun@sj-hospital.org
Classification:
12.8.10 Woundhealing antifibrosis (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
12.8.2 With tube implant or other drainage devices (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
