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Abstract #27618 Published in IGR 12-4
Primary study on cyanoacrylate used in trabeculectomy
Wang T; Zhao M; Yang X-ZInternational Journal of Ophthalmology 2010; 10: 1692-1694
AIM: To observe and investigate the method and clinical effectiveness of using the N-Octyl-Cyanoacrylate/N-Butyl-Cyanoacryl-ate(N-OCA/N- BCA) on sticking scleral flap in trabeculectomy. METHODS: We chose prospective-clinical-contrast study, randomly devided those 40 patients who received glaucoma trabeculectomy into 2 groups: 20 patients 25 eyes in the bonding group using cyanoacrylate to stick scleral flap, 20 patients 28 eyes in the sutures group using 10-0 nylon line to suture scleral flap. We evaluated the benefits of them with respect to surgical effects, responses, complications, intraocular pressure (IOP), vision, field of vision and so on. RESULTS: After following up for 6-24 months, compared the bonding group (25 eyes of 20 cases) with the sutures group (28 eyes of 20 cases), the difference of the postoperative IOP was not statistically significant (P > 0.05); After surgery, in bonding group, 3 eyes' (1 eye on two weeks later, 2 eyes on one month later) IOP >21 mmHg, through local drugs therapy, it fell down to normal level; in sutures group, 2 eyes' (7 days later) IOP >21 mmHg, through local drugs therapy, 1 eye became normal, but another eye failed in this way and took the second surgery six months later; The eyes in two groups mainly tended to form type II blebs according to Kronfeld classification, the functional filtration bleb was 84% and 82% in bonding group and sutures group, respectively; Complications in both groups were few; Vision and field of vision almost had no change after surgery, without statistical significance. CONCLUSION: The using of N-OCA/N-BCA instead of lines to stick scleral flap in trabeculectomy makes the surgery safer and easier, and can surpass sutures to some extent. It is worth spreading and studying for clinical use. LA: Chinese
M. Zhao. Department of Ophthalmology, Chongqing University of Medical Sciences, Chongqing 400016, China. minzhao2002@yahoo.com.cn
Classification:
12.20 Other (Part of: 12 Surgical treatment)