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Abstract #28219 Published in IGR 13-1
Targeting glaucoma beyond intraocular pressure
Rautenstrauss B; Mardin CExpert Review of Ophthalmology 2010; 5: 217-224
Primary open-angle glaucoma, as the most prevalent form of glaucoma, is a complex inherited disorder that affects more than 30 million individuals worldwide. It has become increasingly clear that genetic as well as environmental factors have an impact on the development of this disorder. A number of chromosomal and genetic associations have been reported for primary open-angle glaucoma and juvenile open-angle glaucoma. This review summarizes what is currently known about the underlying genetic predispositions, the currently open-ended questions, and how this may affect our management of this major blinding disease in the future.
B. Rautenstrauss. Medical Genetics Center, Bayerstrasse 3-5, 80335 Munich, Germany. rautenstrauss@mgz-muenchen.de
Classification:
9.2.2 Other risk factors for glaucoma (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)
11.1 General management, indication (Part of: 11 Medical treatment)
1.3 Pathogenesis (Part of: 1 General aspects)