advertisement
This study aimed to assess the influence of age on intraocular pressure (IOP) in a general population. The Blue Mountains eye study assessed 3654 residents aged 49+ years during 1992-1994. IOP was measured using Goldmann applanation tonometry. Subjects with glaucoma, those currently on glaucoma medications, and those with a history of cataract surgery were excluded. IOP was reliably measured in 3260 subjects. Mean IOP was 16.0 mmHg with no significant difference found between males and females (p < 0.89). In univariate analyses, age was positively associated with IOP (p < 0.05). Systolic blood pressure (SBP) was strongly positively associated with IOP (p < 0.001). After adjusting for SBP, there was a trend for IOP to decrease with increasing age (p < 0.051). After further adjusting for other potential confounders (diabetes, glaucoma family history and myopia), age was no longer significantly associated with IOP (p < 0.29). In summary, no evidence was found of an independent age affect on IOP.
Dr. E. Rochtchina, Department of Ophthalmology, Centre for Vision Research, Westmead Hospital, University of Sydney, Sydney, New South Wales, Australia
1.1 Epidemiology (Part of: 1 General aspects)