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Abstract #3413 Published in IGR 4-2
Comparison of the effectiveness of scanning laser polarimetry and optical coherence tomography for estimating optic nerve fibre layer thickness in patients with glaucoma
Furuichi M; Kashiwagi K; Furuichi Y; Tsukahara SOphthalmologica 2002; 216: 168-174
PURPOSE: The effectiveness of scanning laser polarimetry (by the nerve fiber analyzer, NFA) and of optical coherence tomography (OCT) in estimating nerve fiber layer thickness (NFLT) and the correlations between NFLT and cup-to-disc (C/D) ratio or values of mean deviation (MD) from static visual field tests were compared using patients with glaucoma. MATERIAL AND METHODS: Twenty-four eyes from 24 glaucoma patients were enrolled. The NFLT was measured along a circle with a diameter 1.5 times that of the optic disc around the optic disc. The averaged estimated NFLT of the circle or of each quadrantal NFLT (nasal, temporal, superior, inferior) was compared. RESULTS: The covariant indexes measured by the NFA were significantly smaller than those measured by OCT in both the averaged NFLT (p = 0.0002) and in each quadrantal NFLT (p < 0.05). The C/D ratio was significantly correlated with the averaged NFLT when measured by OCT (r = 0.425, p = 0.038), but not by the NFA (r = 0.179, p = 0.407). However, when measured by OCT, these values showed a significant correlation (r = 0.425, p = 0.039). Although both the OCT and NFA data showed significant correlations between NFLT and the MD (p = 0.0002 and p = 0.038, respectively), the OCT data showed a stronger correlation than did the NFA data (r = 0.677 and r = 0.422, respectively). The correlation between the averaged NFLTs obtained by NFA and OCT was not significant (r = 0.289, p = 0.172). CONCLUSIONS: OCT is thought to have an equal or better effectiveness for estimating NFLT, in spite of a lower reproducibility than that of the NFA.
Dr. M. Furuichi, Department of Ophthalmology, Yamanashi Medical University, Yamanashi, Japan
Classification:
2.13 Retina and retinal nerve fibre layer (Part of: 2 Anatomical structures in glaucoma)
6.9.1 Laser scanning (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis)
6.9.2 Optical coherence tomography (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis)