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Abstract #3421 Published in IGR 4-2
Correlation between the retinal nerve fiber layer thickness and the pattern electroretinogram amplitude
Toffoli G; Vattovani O; Cecchini P; Pastori G; Rinaldi G; Ravalico GOphthalmologica 2002; 216: 159-163
OBJECTIVE: To establish a correlation between the retinal nerve fiber layer (RNFL) thickness measured by a scanning laser polarimeter (GDx) and the pattern electroretinogram (p-ERG) amplitudes in a heterogeneous population sample composed of normal subjects, ocular hypertensive and glaucomatous patients. METHODS: One hundred and twelve subjects were considered: 40 glaucomatous patients, 39 ocular hypertensive and 33 normal subjects. All were examined with the GDx, and the RNFL thickness was measured. Transient p-ERG was then recorded. RESULTS: A statistically significant correlation was observed between the RNFL thickness and the p-ERG amplitudes (p < 0.001) by means of linear regression analysis. CONCLUSIONS: The authors observed a strict correlation between the measurements of the RNFL thickness obtained with the GDx and the amplitude of the p-ERG signal. These techniques represent additional objective tools to detect an early glaucomatous damage.
Dr. G. Toffoli, Istituto di Clinica Oculistica, Universita di Trieste, Ospedale Maggiore, Trieste, Italy
Classification:
2.13 Retina and retinal nerve fibre layer (Part of: 2 Anatomical structures in glaucoma)
6.7 Electro-ophthalmodiagnosis (Part of: 6 Clinical examination methods)
6.9.1 Laser scanning (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis)
