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The authors measured retinal nerve fiber layer thickness (NFLT) in 50 normal and 50 glaucomatous eyes, using a Nerve Fiber Analyzer GDx (GDx). The glaucomatous eyes showed a mean deviation of -5 dB or greater with the Humphrey 30-2 program. The following 11 parameters were used: symmetry, superior ratio, inferior ratio, superior/nasal, maximum modulation, ellipse modulation, with the newly introduced parameters: normalized superior area, normalized inferior area, elipse standard deviation, discriminant analysis, and sector analysis. When eyes were defined as abnormal if at least one parameter was abnormal, the sensitivity was 86% and the specificity was 54%. These findings show the potential usefulness of the measurement of NELT using GDx with new parameters in the detection of early glaucoma. LA: Japanese
Dr. K. Yaoeda, Department of Ophthalmology, Niigata University School of Medicine, 1-757 Asahi-machi-dori, Niigata-shi 951-8510, Japan
2.13 Retina and retinal nerve fibre layer (Part of: 2 Anatomical structures in glaucoma)
6.9.1 Laser scanning (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis)