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Abstract #3467 Published in IGR 4-2
Multifocal electroretinograms in early primary open-angle glaucoma
Sakemi F; Yoshii M; Okisaka SJapanese Journal of Ophthalmology 2002; 46: 443-450
PURPOSE: To determine the utility of multifocal electroretinograms (mfERGs) in patients with early primary open-angle glaucoma (POAG) with unilateral visual field abnormalities. METHODS: mfERGs were recorded in 24 eyes of 12 cases of early POAG (stage I for one eye and stage II for the other eye on the Kosaki scale). The implicit times and amplitudes of the second-order kernal totalled for the whole visual field, for the superior and inferior hemifields, and for quadrantic fields of the stage I and II eyes, were compared. RESULTS: Neither the first- nor the second-order kernels of the mfERGs showed any changes reflecting glaucomatous visual field abnormalities. Neither were the implicit times and amplitudes of the second-order kernal totalled for the whole visual field, the superior and inferior hemi-visual fields, and quadrantic visual fields of the stage I and II eyes, significantly different. CONCLUSIONS: The authors conclude that, because the second-order kernal of the mfERG does not correlate with the visual field abnormality in early POAG, the second-order kernel of the mfERG that can be recorded at present is highly unlikely to reflect the function of the ganglion cells in the inner retinal layers.
Dr. M. Yoshii, Department of Ophthalmology, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama Prefecture, 359-8513, Japan
Classification:
6.7 Electro-ophthalmodiagnosis (Part of: 6 Clinical examination methods)