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Abstract #3471 Published in IGR 4-2
The effect of intraocular pressure on ocular hemodynamics in acute angle-closure glaucoma
Dong Y; Zhang W; Song YChinese Ophthalmic Research 2002; 20: 157-159
OBJECTIVE: To analyze the change in ocular hemodynamics in patients with acute angle-closure glaucoma (AACG) at different intraocular pressures (IOP). METHODS: The hemodynamics were measured with color Doppler ultrasonography, including blood velocity and resistance index (RI) of the ophthalmic artery (OA), central retinal artery (CRA), and posterior ciliary artery (PCA) in 30 normal subjects (30 eyes) and 42 patients (42 eyes) with AACG and high IOP, returning to normal level postoperatively. RESULTS: (1) The IOP (> 30 mmHg) and RI of the CRA and PCA in patients with AACG and high IOP was significantly positively correlated (p < 0.01). (2) The hemodynamics of the CRA and PCA in 42 patients with AACG and different IOPs before and after operation were statistically improved (p < 0.01), except for the posterior ciliary artery (PSV) in CRA (p = 0.1406). (3) The hemodynamics of the CRA and PCA in patients with AACG after operation were lower than those in normal subjects (p < 0.05). CONCLUSIONS: During the development of AACG, high IOP can change the introcular hemodynamics. It is suggested that the mechanical and vascular factors interact with each other and lead to damage of the ocular nerve. LA: Chinese
Dr. Y. Dong, Department of Ophthalmology, Second Clinical College, Norman Bethune University of Medical Science, Changchun 130041, China
Classification:
6.11 Bloodflow measurements (Part of: 6 Clinical examination methods)
9.3.1 Acute primary angle closure glaucoma (pupillary block) (Part of: 9 Clinical forms of glaucomas > 9.3 Primary angle closure glaucomas)
