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Abstract #3524 Published in IGR 4-2
Relationship between intraocular pressure and systemic health parameters in a Korean population
Lee JS; Lee SH; Oum BS; Chung JS; Cho BM; Hong JWClinical and Experimental Ophthalmology 2002; 30: 237-241
PURPOSE: This study aimed to evaluate the relationship between intraocular pressure (IOP) and age and obesity, adjusted for systemic health parameters such as sex and mean blood pressure, in a Korean population. METHODS: A total of 13 212 healthy participants underwent automated multiphasic tests, including tonometry, automated perimetry, fundus photography, blood pressure and body mass index (BMI). Six age groups were used, divided by decades ranging from 20-29 years to 70+ years. The association between IOP and systemic health parameters was examined using cross-sectional analysis. RESULTS: The median age of participants was 47.6 years (range, 20-84 years), and 6684 (50.6%) of participants were males. The mean IOP of participants was 15.5 mmHg. The mean IOP, blood pressure, and BMI values were significantly higher in males than in females (p < 0.05). The overall prevalence of ocular hypertension, defined as IOP > 21 mmHg without signs of glaucomatous visual field loss or optic disc damage, was 6.1% in males and 2.5% in females. IOP was associated with mean blood pressure, sex, age, and BMI by multiple regression analysis (p < 0.05). The relationship between IOP and age adjusted for sex, mean blood pressure, and BMI had a significantly negative tendency for both sexes (p < 0.05). Body mass index had a significantly positive relation with IOP after controlling for age, sex and mean blood pressure in males (p < 0.05), but not in females. CONCLUSIONS: In this Korean population, after multiple adjustment, IOP was found to decrease with age and to increase with BMI in males.
Dr. J.S. Lee, Departments of Ophthalmology, Internal Medicine and Preventive Medicine, College of Medicine, Pusan National University, Pusan, and Department of Ophthalmology, College of Medicine, Korea University, Seoul, Korea
Classification:
9.2.2 Other risk factors for glaucoma (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)
