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Abstract #3541 Published in IGR 4-2
Trabecular aspiration in pseudoexfoliative glaucoma: surgery to primarily reduce intraocular pressure
Grub M; Mielke J; Rohrbach JM; Schlote TKlinische Monatsblätter für Augenheilkunde 2002; 219: 353-357
BACKGROUND: Trabecular aspiration has been discussed during the past few years as a new surgical method in the treatment of pseudoexfoliative glaucoma. In this procedure, PEX material, pigment, and detritus are aspirated from the trabecular meshwork. Trabecular aspiration has been evaluated mainly in combination with cataract extraction. This study reports on the authors' first experiences concerning the IOP-reducing effect of trabecular aspiration as a primary surgical method in the management of pseudoexfoliative glaucoma. MATERIAL: Seventeen eyes of 14 patients (seven males, seven females; 12 OD, 5 OS; aged 71 ± 6 years) with pseudoexfoliative glaucoma were included in this study and were operated on by standard trabecular aspiration (vacuum maximum 200 mmHg, 180-270°, five minutes). Success was defined as an IOP reduction of more than 20% and less than 21 mmHg. RESULTS: There was 82% success (14 of 17) on the first postoperative day, 50% after 30 days (eight of 16) and 23% after 180 days (three of 13). IOP was 26.8 ± 8.5 mmHg before surgical intervention, 18.1 ± 11.4 mmHg after one day, 19.1 ± 7.9 mmHg after 30 days, and 19.2 ± 5.2 mmHg after 180 days. Mean quantity of applied antiglaucomatous eye drops was 3.1 ± 0.9 preoperatively, 0.9 ± 1.6 after 1 day, 0.8 ± 1.2 after 30 days, and 1.0 ± 1.3 after 180 days. CONCLUSIONS: Trabecular aspiration achieves a good short-term effect in the reduction of IOP in patients with pseudoexfoliative glaucoma. However, this effect was limited to a few weeks in most patients. Trabecular aspiration as a primary surgical method in the management of pseudoexfoliative glaucoma does not appear to be suitable for long-term IOP reduction. LA: German
Dr. M. Grub, Universitäts-Augenklinik Tübingen, Abteilung 1, Erkrankungen des vorderen und hinteren Augenabschnittes, Tübingen, Germany. matthias.grueb@med.uni-tuebingen.de
Classification:
9.4.4.1 Exfoliation syndrome (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.4 Glaucomas associated with disorders of the lens)
12.20 Other (Part of: 12 Surgical treatment)