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Abstract #3568 Published in IGR 4-2
Latanoprost in hemifacial spasm
Crevits L; Goethals M; Libbrecht N; Paemeleire KProstaglandins & other lipid mediators 2002; 67: 27-30
An empirical observation that the prostaglandin derivate atanoprost caused facial spasms in patients with glaucoma prompted the authors to study latanoprost in non-glaucomatous patients with hemifacial spasms (HFS). This explorative trial followed an open-label, prospective treatment design. At short-term, most patients showed no or only mild improvement, and subsequently needed therapy with Botulinum toxin A. Although these results are not impressive, latanoprost could be considered an interesting alternative in the treatment of patients with HFS and with concomitant glaucoma. A role for prostaglandins in the trigeminofacial reflex is hypothesized.
Dr. L. Crevits, Department of Neurology, Neuro-Ophthalmology Unit, Ghent University Hospital, Belgium. Luc.crevits@rug.ac.be
Classification:
11.4 Prostaglandins (Part of: 11 Medical treatment)
