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Abstract #3621 Published in IGR 4-2
Additive effect of topical nipradilol for normal-tension glaucoma treated by unoprostone or latanoprost
Mizutani M; Takeuchi A; Koike N; Hisada Y; Suga Y; Isokawa H; Nakamura Y; Miyake G; Saito Y; Iwaki MJapanese Journal of Clinical Ophthalmology 2002; 56: 799-803
The authors evaluated the additive effect of topical nipradilol on 15 eyes with normal-tension glaucoma treated by prostaglandin only. In eight eyes, the intraocular pressure (IOP) averaged 16.3 mmHg before unoprostone, 15.0 mmHg (p = 0.259) after unoprostone, and decreased significantly to 13.3 mmHg (p = 0.011) 24 weeks after the start of nipradilol twice daily. In another group of seven eyes, IOP averaged 17.6 mmHg before latanoprost, decreased to 15.4 mmHg (p = 0.002) after latanoprost, and to 13.7 mmHg (p = 0.011) 24 weeks after the start of nipradilol. These findings show that topical nipradilol is effective in normal-tension glaucoma when added to unoprostone or latanoprost. LA: Japanese
Dr. M. Mizutani, Department of Ophthalmology, Aichi Medical University School of Medicine, 21 Karimata Yazako, Aichi-gun Aichi-ken 480-1103, Japan
Classification:
11.3.4 Betablocker (Part of: 11 Medical treatment > 11.3 Adrenergic drugs)
11.4 Prostaglandins (Part of: 11 Medical treatment)