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Abstract #3632 Published in IGR 4-2
Goniotomy for glaucoma secondary to chronic childhood uveitis
Freedman SF; Rodriguez Rosa RE; Rojas MC; Enyedi LBAmerican Journal of Ophthalmology 2002; 133: 617-621
PURPOSE: To evaluate the safety and efficacy of standard goniotomy surgery for young patients with refractory glaucoma associated with chronic childhood uveitis. DESIGN: Interventional case series. METHODS: The authors retrospectively reviewed all goniotomies performed at their institution for patients with a diagnosis of refractory glaucoma associated with chronic childhood uveitis from 1994 to 2000 (this was the first-line surgery for such patients during these years). Uveitis was medically controlled in all cases for at least six weeks before surgery. The main outcome measure was time after surgery without failure. Success was defined as final intraocular pressure (IOP) ≤ 21 mmHg after one or two goniotomies without need for further surgical intervention. Follow-up was ≤ 6 months or until surgical failure. RESULTS: Nineteen goniotomies were performed on 16 eyes (12 patients). Diagnoses included uveitic glaucoma associated with juvenile rheumatoid arthritis, sarcoidosis, and idiopathic uveitis. The mean patient age at first goniotomy was 15.3 years (range, 6.5-30), with mean follow-up 32.4 months (range, 6-84). Cases included were phakic (ten eyes), aphakic (four eyes), and pseudophakic (two eyes). The mean preoperative IOP was 32.3 ± 4.6 mmHg. Surgical success was achieved in 12 of 16 (75%) eyes with a mean postoperative IOP of 12 ± 2.5 mmHg for these eyes (mean IOP reduction, 20.0 mmHg, p < 0.0001). In ten of 16 eyes (60%), surgical success was achieved after a single goniotomy. Uveitis was stable in all patients after the early postoperative period. Successful eyes used, on average, 1.4 ± 1.1 glaucoma medications after goniotomy. Complications were mild and included transient hyphema in nine cases (56%) and worsening of a preexisting cataract in a single case (6%). CONCLUSIONS: Goniotomy represents a safe and effective first-line surgery for young patients with refractory glaucoma associated with chronic uveitis, although the majority of patients require glaucoma medication after the procedure.
Dr. S.F. Freedman, Duke University Eye Center, Durham, NC 27710, USA. freed003@mc.duke.edu
Classification:
12.9 Trabeculotomy, goniotomy (Part of: 12 Surgical treatment)
