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Abstract #45579 Published in IGR 13-2
Patterns of Damage in Chronic Angle-Closure Glaucoma Compared to Primary Open-Angle Glaucoma
Nouri-Mahdavi K; Supawavej C; Bitrian E; Giaconi JA; Law SK; Coleman AL; Caprioli JAmerican Journal of Ophthalmology 2011;
Purpose: To compare patterns of damage in chronic angle-closure glaucoma (CACG) to a control group of patients with primary open-angle glaucoma (POAG). Design: Retrospective cross-sectional study. Methods: setting: Academic tertiary-care glaucoma clinic. study population: Thirty-two eyes of 32 patients with CACG and good-quality Heidelberg Retina Tomograph (HRT) images (pixel standard deviation <50 (mu)m) and stereoscopic disc photographs within 1 year of a visual field showing reproducible glaucomatous field loss (mean deviation (greater-than or equal to)-15.0 dB) were enrolled. Control eyes with POAG meeting similar criteria and matched for severity of field loss ((plus or minus)1 dB) and race were selected. outcome measures: Presence of focal rim loss ((less-than or equal to)1 clock hour), HRT stereometric parameters, and extent and location of field loss. Results: The average mean deviation was -5.1 dB in both groups. Patients with CACG were more hyperopic (0.6 (plus or minus) 0.4 vs -1.4 (plus or minus) 0.5 D; P < .001) and had higher IOP at the time of imaging (15.8 (plus or minus) 0.8 vs 13.9 (plus or minus) 0.9 mm Hg; P = .015). Focal disc damage was not less frequent in PACG eyes (19% vs 24%; P = .545). Eyes with PACG had smaller cup area, cup volume, and mean cup depth and larger rim/disc area ratio (P < .05 for all), which persisted after adjusting for disc size, age, refractive error, and IOP. The average ((plus or minus)SD) number of abnormal test locations was similar in the 2 groups (P = .709), although CACG eyes were less likely to have paracentral points involved (47% vs 72%; P = .04). Conclusions: Patterns of glaucomatous damage seem to be different in CACG compared with POAG. This difference in patterns of damage may adversely affect detection of early disease or its progression in CACG.
K. Nouri-Mahdavi. Glaucoma Division, Jules Stein Eye Institute, David Geffen School of Medicine, University of Califor, . Email: nouri-mahdavi@jsei.ucla.edu
Classification:
9.3.2 Chronic primary angle closure glaucoma (pupillary block) (Part of: 9 Clinical forms of glaucomas > 9.3 Primary angle closure glaucomas)
6.9.1.1 Confocal Scanning Laser Ophthalmoscopy (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis > 6.9.1 Laser scanning)
6.8.2 Posterior segment (Part of: 6 Clinical examination methods > 6.8 Photography)
6.6.2 Automated (Part of: 6 Clinical examination methods > 6.6 Visual field examination and other visual function tests)
