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Abstract #45753 Published in IGR 13-2
The ahmed baerveldt comparison study: Methodology, baseline patient characteristics, and intraoperative complications
Barton K; Gedde SJ; Budenz DL; Feuer WJ; Schiffman JOphthalmology 2011; 118: 435-442
Purpose The Ahmed Baerveldt Comparison (ABC) Study compares the long-term outcomes and complications of the Ahmed glaucoma valve (AGV; model FP7; New World Medical, Los Ranchos, CA) and the Baerveldt glaucoma implant (BGI; model 101-350; Abbott Medical Optics, Abbott Park, IL). Design Multicenter, randomized, controlled clinical trial. Participants Two hundred seventy-six glaucoma patients at 16 clinical centers worldwide who were 18 to 85 years of age with inadequately controlled intraocular pressure (IOP; <18 mmHg) in whom placement of an aqueous shunt was planned. Methods Study patients were randomized to undergo implantation of an AGV or a BGI. Main Outcome Measures Failure, defined as IOP >21 mmHg or not reduced by 20% less than baseline or IOP (less-than or equal to)5 mmHg (2 consecutive visits after 3 months), additional glaucoma surgery, removal of the implant, or loss of light perception vision. Results A total of 276 patients were enrolled between October 2006 and April 2008, including 143 in the AGV group and 133 in the BGI group. The mean age(plus or minus)standard deviation (SD) of patients enrolled was 63(plus or minus)14 years, and 52% were male. The mean baseline IOP(plus or minus)SD was 31.5(plus or minus)11.8 mmHg. Except for a 13% higher prevalence of hypertension in the AGV group, no significant differences in baseline demographic or ocular characteristics were observed between the study groups. Intraoperative complications occurred in 11 (8%) patients in the AGV group and in 16 (12%) patients in the BGI group (P = 0.31). Conclusions The ABC Study should yield valuable prospective data comparing 2 commonly used aqueous shunts in clinical practice.
D. L. Budenz. Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, 900 NW17th Street, Miami, FL 33136, United States.
Classification:
12.8.2 With tube implant or other drainage devices (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
