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Purpose: To assess whether retinal nerve fiber layer (RNFL) thickness value obtained with optical coherence tomography (OCT) in ocular hypertension patients can predict glaucomatous changes in visual field over a 2-year period. Methods: This comparative analysis included 76 eyes: 36 ocular hypertension (OHT) and 40 healthy. The OCT parameter RNFL thickness and Octopus automated perimetry (SAP) were performed in ocular hypertension and healthy eyes at baseline and after 2 years. Results: In ocular hypertension group, 6 (16.6%) eyes developed SAP glaucomatous abnormalities in 2-year period. Comparison of RNFL thickness between OHT eyes with and without glaucomatous changes and healthy eyes showed statistically significant thinning of RNFL in the inferior quadrant at baseline in OHT eyes with SAP glaucomatous changes. Conclusion: Thinner OCT obtained inferior RNFL in OHT eyes is associated with future development of perimetric glaucoma changes.
S. Popovic-Suic. Klinika za Ocne Bolesti Klinickog Bolnickog Centra Zagreb, Kispaticeva 12, 10000 Zagreb, Croatia. Email: spopovic@kbc-zagreb.hr
6.9.2.2 Posterior (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis > 6.9.2 Optical coherence tomography)
6.6.2 Automated (Part of: 6 Clinical examination methods > 6.6 Visual field examination and other visual function tests)