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Abstract #45970 Published in IGR 13-2
The effect of early posttrabeculectomy intraocular pressure spike in the collaborative initial glaucoma treatment study
Chen PP; Musch DC; Niziol LMJournal of Glaucoma 2011; 20: 211-214
Purpose: To examine effects of early postoperative intraocular pressure (IOP) spike in patients undergoing primary trabeculectomy in the Collaborative Initial Glaucoma Treatment Study. Patients And Methods: We identified patients with IOP spike (greater-than or equal to)5 mm Hg above the baseline IOP on postoperative day 1 and those without IOP increase. The mean deviation (MD), pattern standard deviation (PSD), and corrected PSD of the visual field (VF) were compared at 6 months and years 1, 2, 3, and 5 after surgery, as was the Iop. Results: Seventeen of 300 patients (5.7%) had IOP spike. After controlling for baseline VF severity in a generalized linear regression model that addressed change in MD, PSD, and corrected PSD, or in a logistic regression model for (greater-than or equal to)3 dB of MD change, comparison between the groups revealed no significant difference at all time points examined (P>0.05). Patients with IOP spike had significantly higher mean IOP at years 3 and 5 of follow-up (P(less-than or equal to)0.04). Conclusions: Among Collaborative Initial Glaucoma Treatment Study patients, early posttrabeculectomy IOP spike (greater-than or equal to)5 mm Hg above baseline IOP was not associated with subsequent VF loss, but was associated with significantly higher IOP during long-term follow-up.
P. P. Chen. Department of Ophthalmology, University of Washington, Box 359608, 325 Ninth Avenue, Seattle, WA 98104-2499, United States.
Classification:
12.8.1 Without tube implant (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
