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Abstract #46077 Published in IGR 13-2
Central corneal thickness in children
Bradfield Y; Repka M; Kaminski BJournal of AAPOS 2011; 15: 2-3
Purpose: To report the central corneal thickness (CCT) in healthy white, African American, and Hispanic children from birth to 17 years of age. Methods: Children from birth to 17 years of age with normal corneas had CCT measured in the clinic or under general anesthesia using a single model of pachymeter. Results: 2079 children were studied (807 White, 494 Hispanic, 474 African- American, 177 Asian, and 127 of mixed, other or unknown race). African-American children had thinner corneas on average than those of both white (p<.001) and Hispanic children (p<.001) by approximately 20 (mu)m. The range of normal CCT between the 5th and 95th reference percentiles at any age is about 120 mm. Thicker median CCT was observed with each successive year of age from 1 to 11 years, with differences from the prior year steadily decreasing and reaching a plateau at 573 mm in white and Hispanic children and 551 mm in African American children. For every 100 mm of thicker CCT measured, the intraocular pressure was 1.5 mm Hg higher on average (p<0.001). Discussion: Median CCT increases with age from 1 to 11 years with the greatest increase in the youngest subjects. African American children have thinner central corneas than white and Hispanic children, while white and Hispanic children demonstrate similar CCT. Conclusions: For a CCT falling within the 5th and 95th percentiles for age, the effect of CCT causes variation in IOP of no more than 2 mm Hg and should not influence the decision about the presence or absence of glaucoma.
Y. Bradfield.
Classification:
9.1.2 Juvenile glaucoma (Part of: 9 Clinical forms of glaucomas > 9.1 Developmental glaucomas)
2.2 Cornea (Part of: 2 Anatomical structures in glaucoma)
6.1.3 Factors affecting IOP (Part of: 6 Clinical examination methods > 6.1 Intraocular pressure measurement; factors affecting IOP)
