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1 General aspects (0)   1.1 Epidemiology (14)   1.2 Population genetics (0)   1.3 Pathogenesis (2)   1.4 Quality of life (11)   1.5 Glaucomas as cause of blindness (10)   1.6 Prevention and screening (13) 2 Anatomical structures in glaucoma (0)   2.1 Conjunctiva (12)   2.2 Cornea (30)   2.3 Sclera (2)   2.4 Anterior chamber angle (8)   2.5 Meshwork (0)     2.5.1 Trabecular meshwork (17)     2.5.2 Schlemms canal (1)     2.5.3 Scleral outlet channels (2)   2.6 Aqueous humor dynamics (0)     2.6.1 Production (0)     2.6.2 Outflow (0)       2.6.2.1 Trabecular meshwork (5)       2.6.2.2 Uveoscleral (1)     2.6.3 Compostion (3)   2.7 Episcleral veins and venous pressure (4)   2.8 Iris (5)   2.9 Ciliary body (5)   2.10 Lens (0)   2.11 Vitreous body (0)   2.12 Choroid, peripapillary choroid, peripapillary atrophy (7)   2.13 Retina and retinal nerve fibre layer (30)   2.14 Optic disc (28)   2.15 Optic nerve (2)   2.16 Chiasma and retrochiasmal central nervous system (6)   2.17 Stem cells (1)   2.20 Other (0) 3 Laboratory methods (0)   3.1 Microscopy (3)   3.2 Electron microscopy (0)   3.3 Immunohistochemistry (6)   3.4 Molecular genetics (0)     3.4.1 Linkage studies (3)     3.4.2 Gene studies (39)   3.5 Molecular biology incl. 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pharmacoeconomics (4) 15 Miscellaneous (37)

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Abstract #46081 Published in IGR 13-2

Unilateral congenital glaucoma in a child with optic nerve aplasia

Floyd MS; Kwon YH; Shah S; Benson C; Longmuir SQ
Journal of AAPOS 2011; 15: 200-202

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Unilateral optic nerve aplasia is a rare, nonhereditary defect associated with anterior chamber malformations and other ocular malformations. We report the case of an 8 1/2-week-old boy with unilateral optic nerve aplasia who was diagnosed with glaucoma on presentation with corneal edema and an intraocular pressure of 36 mm Hg. The cornea edema cleared after a trabeculotomy, and subsequent fundus examination revealed optic nerve aplasia that was confirmed with magnetic resonance imaging. Intraocular pressure remained well-controlled with 7 1/2 months of follow-up. To our knowledge, this is the first documented case of optic nerve aplasia associated with glaucoma at presentation.

S. Q. Longmuir. University of Iowa Hospitals and Clinics, Department of Ophthalmology, Iowa City, IA, United States. Email: Susannah-longmuir@uiowa.edu

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Classification:

9.1.1 Congenital glaucoma, Buphthalmos (Part of: 9 Clinical forms of glaucomas > 9.1 Developmental glaucomas)
9.4.5 Glaucomas associated with disorders of the retina, choroid and vitreous (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)
2.15 Optic nerve (Part of: 2 Anatomical structures in glaucoma)

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