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Abstract #46254 Published in IGR 13-2
Pulsatile ocular blood flow in subjects with sleep apnoea syndrome
Nowak MS; Jurowski P; Gos R; Prost ME; Smigielski JArchives of Medical Science 2011; 7: 332-336
Introduction: The aim of the study was to determine the correlation between pulsatile ocular blood flow (POBF) and sleep apnoea syndrome (SAS). Material and methods: Patients were recruited from those who underwent polysomnography in the "Sleep Unit" of the physiology department (Medical University, Lodz, Poland). A total of 52 Caucasian patients, 34 with SAS and 18 age- and gender-matched controls, were included in the study. Comprehensive ophthalmic examination included the pulsatile ocular blood flow (POBF) measurements, disc analysis with Heidelberg Retina Tomograph II and Oculus Centerfield computerized perimetry as well as the best visual acuity, a slit lamp and indirect ophthalmoscopic evaluation of anterior and posterior segments and applanation tonometry. Results: The observed prevalence of glaucoma in SAS patients was 5.9% (2 of 34). The mean values of POBF were 1069.21 (plus or minus)235.94 (mu)l/min in the SAS group and 1061.78 (plus or minus)174.63 (mu)l/min in the control group. The study revealed that the differences of mean POBF between the SAS patients and the control group were not statistically significant: Mann-Whitney U-test p > 0.05. No correlations were found between sleep apnoea syndrome and mean intraocular pressure (IOP), mean retinal nerve fibre layer (RNFL) thickness and visual field mean defect (MD). Conclusions: No correlation was found between pulsatile ocular blood flow and sleep apnoea syndrome. Although some previous studies found an association between IOP, MD, RNFL thickness and sleep apnoea syndrome, our study did not confirm that. However, a high prevalence of glaucoma was found among SAS patients in Poland.
M. S. Nowak. Department of Ophthalmology and Visual Rehabilitation, Medical University of Lodz, 113 Zeromskiego, 90-549 Lodz, Poland. Email: michaelnovak@interia.pl
