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Abstract #46271 Published in IGR 13-2
Elevated laser flare values correlate with complicated course of anterior uveitis in patients with juvenile idiopathic arthritis
Christoph T; Carsten H; Martin R; Arnd HActa Ophthalmologica 2011;
Purpose: To evaluate the prognostic value of anterior chamber (AC) laser flare (LF) in uveitis associated with juvenile idiopathic arthritis (JIA). Methods: Monocentre, retrospective study of 150 JIA children (girls n=107, 71.3%) with unilateral or bilateral chronic anterior uveitis (statistical analysis of one eye per patient). LF values (KOWA FM-500), visual acuity, intraocular pressure, glaucoma treatment and uveitis complications were investigated longitudinally. Results: Patients were followed up for a mean of 8.7months (range 1-36). High LF values correlated with poor visual acuity (p<0.0001). Patients with low LF values (LF(less-than or equal to)20photon units per millisecond) less often required glaucoma medication (p=0.0005) or surgery (p=0.01) and showed a lower prevalence of cataract, band keratopathy, posterior synechiae, epiretinal membrane, optic disc oedema and glaucoma/ocular hypertension (p<0.05, each). Baseline LF>20photon units per millisecond was a better prognosticator for the development of subsequent complications than baseline AC cells (p=0.04). Conclusions: High LF values in patients with JIA uveitis are associated with poor vision and a higher prevalence of uveitis complications.
H. Arnd. Department of Ophthalmology, St. Franziskus Hospital, Hohenzollernring 74, 48145 Muenster, Germany, . Email: arnd.heiligenhaus@uveitis-zentrum.de
Classification:
9.4.6 Glaucomas associated with inflammation, uveitis (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)
9.4.15 Glaucoma in relation to systemic disease (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)
