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Abstract #46308 Published in IGR 13-2
Comparison of stereo disc photographs and alternation flicker using a novel matching technology for detecting glaucoma progression
Radcliffe NM; Sehi M; Wallace IB; Greenfield DS; Krupin T; Ritch ROphthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye 2010; 41: 629-634
To compare agreement of automated alternation flicker and serial stereophotograph inspection for detection of progressive glaucoma. Serial photographs of patients with glaucoma with at least 36 months of follow-up and perimetry every 4 months were assessed by four graders using predefined criteria with both flicker and stereophotography. The main outcome measure was progressive neuroretinal rim deterioration as identified by each technique. Forty eyes (20 patients) were included and 12 eyes progressed with perimetry. Using stereophotography, the overall agreement (kappa (plus or minus) standard error) was 0.19 (plus or minus) 0.06 for rim change, 0.78 (plus or minus) 0.06 for disc hemorrhage, and -0.04 (plus or minus) 0.06 for vessel movement. Using flicker, the overall agreement was similar for rim change (0.28 (plus or minus) 0.06; P = .29), worse for disc hemorrhage (0.43 (plus or minus) 0.06; P < .001), and better for vessel movement (0.22 (plus or minus) 0.06; P = .002). The agreement between perimetric and disc progression was similar using stereophotography (0.10 (plus or minus) 0.05) and flicker (0.19 (plus or minus) 0.05; P = .20). Agreement between flicker and stereophotography was similar.
N.M. Radcliffe. Einhorn Clinical Research Center, New York Eye and Ear Infirmary, New York, NY, USA. Email: nmr9003@med.cornell.edu
Classification:
6.30 Other (Part of: 6 Clinical examination methods)
6.8.2 Posterior segment (Part of: 6 Clinical examination methods > 6.8 Photography)
6.20 Progression (Part of: 6 Clinical examination methods)
