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PURPOSE: To examine the relation between Visual Function Index-14 (VF-14) scores and VA by accounting for concurrent ocular comorbidities, effect of the better seeing eye (BSE), and VA before and after cataract surgery. DESIGN: Prospective cohort study. PARTICIPANTS: A total of 4335 patients with cataract who completed the VF-14 before and after cataract surgery. METHODS: Collaborating clinicians provided demographic and clinical data before and after cataract surgery. Lowess curves, general linear models, and Spearman correlation coefficients were used to study the relation between the VF-14 and the VA. MAIN OUTCOME MEASURES: Scores in the VF-14 preintervention, change in VF-14 after surgery, VA before surgery, and VA change after surgery. RESULTS: General linear models and Spearman correlation coefficients showed a significant (P < 0.0001) association between VF-14 score and VA (measured in decimal fraction) when the preoperative VA was ≤0.5 (20/40) and no association (P > 0.4020) when the VA was >0.5 (20/40). Small VA gains (≤0.5) after surgery only led to significant gains (P < 0.0001) in functionality in patients with other ocular pathologies and whose BSE was the surgical eye. Gains in VA >0.5 had a significant (P < 0.02) effect on VF-14 change scores in most patients. CONCLUSIONS: The VF-14 seems to be more sensitive when the preoperative VA is <0.5 (20/40), especially in patients whose BSE is the surgical eye. The VF-14 seems responsive to increases in VA if the gains exceed 0.5. For gains <0.5, the VF-14 seems unresponsive, except for patients with other ocular pathologies in whom the BSE before and after surgery is the surgical eye.
CIBER Epidemiology and Public Health, Hospital Galdakao-Usansolo, Galdakao, Bizkaia, Spain.
1.4 Quality of life (Part of: 1 General aspects)
1.1 Epidemiology (Part of: 1 General aspects)