advertisement
Abstract #46453 Published in IGR 13-3
Prophylactic Selective Laser Trabeculoplasty in the Prevention of Intraocular Pressure Elevation after Intravitreal Triamcinolone Acetonide Injection
Bozkurt E; Kara N; Yazici AT; Yuksel K; Demirok A; Yilmaz OF; Demir SAmerican Journal of Ophthalmology 2011;
Purpose: To evaluate the prophylactic efficacy of selective laser trabeculoplasty for preventing an increase in intraocular pressure (IOP) after intravitreal triamcinolone acetonide injection. Design: Prospective, comparative, interventional case series. Methods: We studied 31 eyes with a baseline IOP of 21 mm Hg or more of 31 patients for which intravitreal triamcinolone acetonide injection was planned for diabetic macular edema. The patients were divided into 2 groups, a study group and control group. The study group comprised 15 eyes of 15 patients that underwent selective laser trabeculoplasty a mean of 8.3 (plus or minus) 4.1 days before intravitreal triamcinolone acetonide injection. The control group comprised 16 eyes of 16 patients who underwent only intravitreal triamcinolone acetonide injection. Main outcomes measures were mean IOP and number of patients requiring antiglaucomatous therapy. Results: Mean baseline IOP was 21.6 (plus or minus) 0.9 mm Hg in the study group and 21.5 (plus or minus) 0.8 mm Hg in the control group (P = .98). Mean IOP at 1 day after injection was 17.0 (plus or minus) 2.0 mm Hg in the study group and 19.5 (plus or minus) 4.3 mm Hg in the control group (P = .23). Mean IOP at 1 week after injection was 16.9 (plus or minus) 1.7 mm Hg and 18.4 (plus or minus) 4.0 mm Hg, respectively (P = .49); mean IOP at 1 month after injection was 16.4 (plus or minus) 1.5 mm Hg and 20.8 (plus or minus) 5.6 mm Hg, respectively (P = .003); mean IOP at 3 months after injection was 15.8 (plus or minus) 2.5 mm Hg and 18.3 (plus or minus) 5.5 mm Hg, respectively (P = .01); and mean IOP at 6 months after injection was 15.7 (plus or minus) 1.4 mm Hg and 17.1 (plus or minus) 1.5 mm Hg, respectively (P = .03). The number of patients requiring antiglaucomatous therapy during follow-up was 0 of 15 eyes in the study group and 8 of 16 eyes in the control group (P = .001). Conclusions: The IOP elevation after intravitreal triamcinolone acetonide injection may be prevented by performing selective laser trabeculoplasty before intravitreal triamcinolone acetonide injection, especially in cases with a baseline IOP of 21 mm Hg or more.
N. Kara. Beyoglu Eye Research and Education Hospital, Istanbul, Turkey, .
Classification:
12.4 Laser trabeculoplasty and other laser treatment of the angle (Part of: 12 Surgical treatment)
11.15 Other drugs in relation to glaucoma (Part of: 11 Medical treatment)
9.4.11.5 Glaucomas associated with vitreoretinal surgery (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.11 Glaucomas following intraocular surgery)
