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Abstract #46659 Published in IGR 13-3
Five-year incidence of visual impairment and blindness in adult Chinese: The Beijing eye study
You QS; Xu L; Yang H; Wang YX; Jonas JBOphthalmology 2011; 118: 1069-1075
Purpose To describe the cumulative 5-year incidence of visual impairment and blindness in adult Chinese in greater Beijing. Design Population-based study. Participants The Beijing Eye Study 2006 included 3251 subjects who had participated in the Beijing Eye Study 2001 and returned for re-examination. Methods Using the World Health Organization (WHO) definition, low vision and blindness were defined as best corrected visual acutiy (BCVA) <20/60 to 20/400 and as BCVA <20/400 in the better-seeing eye, respectively. Using the United States standard, low vision and blindness were defined as BCVA <20/40 to 20/200 and as BCVA <20/200 in the better-seeing eye, respectively. Main Outcome Measures Incidence of low vision and blindness. Results Visual acuity measurements were available for 3249 (99.9%) participants. Using WHO and United States definitions, the incidences of low vision and blindness were 0.5(plus or minus)0.1% (mean(plus or minus)standard error) and 0.1(plus or minus)0.04%, and 1.1(plus or minus)0.2% and 0.1(plus or minus)0.04%, respectively. In multivariate analysis, incidence of BCVA visual impairment or blindness increased significantly with greater age (P = 0.01), but was not associated with gender, region, or level of education. Causes of BCVA visual impairment or blindness were cataract (39%), glaucoma (17%), and degenerative myopia (11%). Using the WHO and the United States criteria, incidences of low vision and blindness based on presenting visual acuity, were 1.7(plus or minus)0.2% and 0.1(plus or minus)0.06%, and 3.8(plus or minus)0.3% and 0.2(plus or minus)0.08%, respectively. Incidence of visual impairment or blindness (presenting visual acuity, WHO definition) increased significantly with higher age (P<0.001) and less education (P = 0.018) and was greater in women (P = 0.015). The major cause of presenting VA visual impairment or blindness was undercorrected refractive error (76%). Conclusions In adult Chinese in greater Beijing, the 5-year cumulative incidence of BCVA visual impairment or blindness was 0.6(plus or minus)0.1% (BCVA in better-seeing eye, <20/60) or 1.7(plus or minus)0.2% (presenting VA in better-seeing eye, <20/60), which increased significantly with age. Measured as presenting VA, this also was associated with female gender and rural region. The major cause (76%) of decreased presenting VA was undercorrected refractive error, followed by cataract. Treating undercorrection of refractive error may be the easiest and most efficient method to improve vision in this community. Financial Disclosure(s) Proprietary or commercial disclosure may be found after the references.
L. Xu. Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, 17 Hougou Lane, Chong Wen Men, 100005 Beijing, China.
Classification:
1.5 Glaucomas as cause of blindness (Part of: 1 General aspects)
1.1 Epidemiology (Part of: 1 General aspects)