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Aims or Purpose To evaluate short-term changes in optic nerve head topography and visual field induced by surgical reduction of intraocular pressure. Methods A prospective study was performed on 56 eyes of 56 patients with uncontrolled primary open-angle glaucoma despite maximum medical therapy, which underwent trabeculectomy. Optic nerve head evaluations by means of Heidelberg Retina Tomograph, and visual field tests were performed pre-operatively, and at 3 and 6 months after surgery. Differences in intraocular pressure, visual field indices, and Heidelberg Retina Tomograph parameters were evaluated with the t-test for paired data. A linear regression model was calculated to analyze the relationship between intraocular pressure reduction and visual field changes, and optic nerve head changes. Results Mean intraocular pressure decreased from 24.45.0 mm Hg to 12.13.1 mm Hg (month 3, P0.001), and 10.62.8 mm Hg (month 6, P0.001) after trabeculectomy. Mean retinal nerve fiber layer thickness (baseline, 0.190.034; month 3, 0.240.039, P0.05; month 6, 0.210.037, P0.05) showed a statistical significant change compared with baseline values. Conclusions In this 6-months study, a significant increase in retinal nerve fiber layer thickness was detected after glaucoma filtration surgery.
M. Figus. Via B. Buozzi, 19, 55045 Pietrasanta (Lucca), Italy.
12.8.1 Without tube implant (Part of: 12 Surgical treatment > 12.8 Filtering surgery)
6.6.2 Automated (Part of: 6 Clinical examination methods > 6.6 Visual field examination and other visual function tests)
2.14 Optic disc (Part of: 2 Anatomical structures in glaucoma)