advertisement
Abstract #46819 Published in IGR 13-3
Correlation between pupil diameter and angle configuration in the dark room provocative test
Li D; Wang N; Wang B; Wang T; Li S; Chen L; Mu DJournal of Glaucoma 2011; 20: 331-335
Purpose: To study the associations between changes in pupil diameter and in the anterior chamber angle configuration during the dark room provocative test. Methods: The study included 70 suspects of primary angle closure (study group) and 40 normal participants (control group). Using anterior-segment optical coherence tomography (AS-OCT), we measured the anterior chamber angle configuration and pupil diameter at 3 minutes and at 1.5 hours of dark adaptation. Results: In the study group, the mean number of closed angle segments was significantly (P<0.001) higher at 3 minutes of dark adaptation (3.9(plus or minus)2.3) than at room light conditions (2.6(plus or minus)2.2) or at 1.5 hours of dark adaptation (3.1(plus or minus)2.1), with no statistically significant (P>0.05) difference between the 2 latter values. In the study group, the pupil diameter was significantly associated with the number of closed angle segments at 3 minutes of dark adaptation (P<0.01), but not at 1.5 hours of dark adaptation (P=0.13). Defined as an increased number of closed angle segments, the dark room test was positive in a significantly higher number of participants at 3 minutes than at 1.5 hours of dark adaptation [44 (63%) eyes vs. 31 (44%) eyes; P<0.05]. Final interocular pressure was statistically better correlated with the angle configuration segments assessed at 3 minutes (correlation coefficient r(2)=0.33) than at 1.5 hours of dark adaptation (r(2)=0.21). Conclusions: After short-term dark adaptation of 3 minutes, the assessment of the anterior chamber angle configuration by AS-OCT is more reliable than as if carried out after a long-term dark adaptation and may be used to identify suspects of primary angle closure.
N. Wang. Tongren Eye Center, Beijing Tongren Hospital, Capital University of Medical Sciences, NO. 2 Chongnei Street, 100730 Beijing, China.
Classification:
6.13 Provocative tests (Part of: 6 Clinical examination methods)
