advertisement
Abstract #46867 Published in IGR 13-3
Intraocular pressure and central corneal thickness in premature and full-term newborns
Uva MG; Reibaldi M; Longo A; Avitabile T; Gagliano C; Scollo D; Lionetti E; Reibaldi AJournal of AAPOS 2011;
Purpose: To evaluate the intraocular pressure (IOP) and central corneal thickness (CCT) in premature and full-term newborns. Methods: IOP and CCT were determined in 33 premature (mean [(plus or minus) SD] gestational age 31 (plus or minus) 3 weeks, mean birth weight 1474 (plus or minus) 354 g) and in 33 full-term white newborns (mean gestational age 39 (plus or minus) 1 weeks, mean birth weight 2763 (plus or minus) 574 g). The mean age after birth at measurement was respectively 3 (plus or minus) 1 weeks and 1 (plus or minus) 1 weeks. Infants with any ocular abnormalities, such as corneal and iris alterations, congenital cataract, retinopathy, glaucomatous corneal and optic disk changes (horizontal corneal diameter >10 mm Hg, C/D >0.4), or familial congenital glaucoma were excluded. IOP was determined with the use of only topical anesthesia with a Tono-Pen XL tonometer and a wire lid retractor, and then CCT was determined by means of a portable pachymeter. Results: Mean IOP was 18.9 (plus or minus) 3.7 mm Hg (range, 13-25) in premature and 17 (plus or minus) 2.6 mm Hg (range, 12-22) in full-term newborns (P = 0.018 after correction by age after birth). Mean CCT was 599 (plus or minus) 36 (mu)m (range, 524-720 (mu)m) in premature infants and 576 (plus or minus) 26 (mu)m (range, 489-650 (mu)m) in the full-term group (P < 0.001 after correction by age after birth). Multivariate analysis showed that IOP increased with increasing CCT (P = 0.025) and that CCT declined with increasing birth weight (P = 0.026). Conclusions: In premature newborns, IOP measurements were slightly greater than in full-term newborns because of an increased CCT.
A. Longo. First Eye Clinic, University of Catania, Catania, Italy, .
Classification:
2.2 Cornea (Part of: 2 Anatomical structures in glaucoma)
6.1.3 Factors affecting IOP (Part of: 6 Clinical examination methods > 6.1 Intraocular pressure measurement; factors affecting IOP)
9.1.1 Congenital glaucoma, Buphthalmos (Part of: 9 Clinical forms of glaucomas > 9.1 Developmental glaucomas)