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Abstract #46937 Published in IGR 13-3
The use of optical coherence tomography for identifying retinal nerve fiber layer progressive damage
Danielescu C; Chiselita DOftalmologia 2010; 54: 109-114
To identify threshold values above which the intersession reduction of the retinal nerve fibers layer (RNFL) can be considered significant. In 79 eyes (41 patients) we have performed RNFL measurements with the Stratus OCT twice in the same session. The differences between these measurements were used to calculate the test-retest variability (on clock hours, quadrants and the average RNFL thickness) using the formula: Test-retest variability = 1.96 x standard deviation (95% confidence) The resulted "threshold values" were used to identify the possible progression in a study group of 119 eyes (61 patients), followed for an average of 2 years. RNFL reduction exceeding the "threshold values" in 2 consecutive sessions was noticed in 18 eyes (15.12%). 12 eyes (10.08%) have fulfilled this criterion on 2 or more clock hours. 3 patients have had the criterion present on both eyes. This appears to be a plausible method for identifying the progression of structural damage in glaucoma, deserving further researches for validation. LA: Romanian
C. Danielescu. Clinica Oftaprof Iasi.
Classification:
6.9.2.2 Posterior (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis > 6.9.2 Optical coherence tomography)
2.13 Retina and retinal nerve fibre layer (Part of: 2 Anatomical structures in glaucoma)
6.20 Progression (Part of: 6 Clinical examination methods)