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Abstract #47086 Published in IGR 13-3
Prevalence and risk factors for angle-closure disease in a rural Northeast China population: A population-based survey in Bin County, Harbin
Qu W; Li Y; Song W; Zhou X; Kang Y; Yan L; Sui H; Yuan HActa Ophthalmologica 2011; 89: e515-e520
Purpose: To estimate the prevalence of primary angle-closure glaucoma (PACG), primary angle closure (PAC) and primary angle-closure suspect (PACS) and associated risk factors for PACG in a rural population in Northeast China. Methods: A population-based survey was conducted in Bin County, Harbin, Northeast China. Glaucoma was diagnosed using the International Society of Geographical and Epidemiological Ophthalmology (ISGEO) criteria. All subjects underwent a complete ophthalmic examination. Results: A total of 4956 (86.01%) of 5762 subjects aged 40 years or older were examined. The mean intraocular pressure (IOP) of the right eyes was 14.0 mmHg. The mean vertical cup-to-disc ratio of the right and the left eyes was 0.31 and 0.31, respectively. The prevalence of PACG, PAC and PACS was 1.57% [95% confidence interval (CI), 1.469-1.671], 1.33% (95% CI, 1.236-1.424), and 4.68% (95% CI, 4.541-4.819), respectively. Among all PACG subjects, 42 (53.84%) had elevated IOP >21 mmHg in either eye and 37 (47.44%) had been treated by laser, surgical iridectomy or trabeculectomy. Sixty-four subjects (82.05%) had vision impairment of varying degrees. Multivariate analysis revealed that old age, family history of PACG, constipation and IOP were significant independent risk factors. Conclusions: Primary angle-closure glaucoma was a disease of high prevalence in rural Northeast China. Old age, family history of PACG, constipation and IOP were significant independent risk factors for PACG.
H. Yuan. Department of Ophthalmology, 2nd Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang 150086, China.
Classification:
1.1 Epidemiology (Part of: 1 General aspects)
9.2.2 Other risk factors for glaucoma (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)
