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Purpose: To investigate the effect of change of body posture from supine to lateral decubitus position (LDP) on intraocular pressure (IOP) in healthy young subjects. Methods: We evaluated 38 eyes of 19 healthy young Korean subjects. IOP was measured using Tonopen XL((registered trademark)) in both eyes in the sitting and supine position, 5 and 30min after right LDP and 5min after returning to the supine position. A week later, IOP was measured in the same sequence except that the subjects assumed the left LDP. The eye on the lower side in the LDP was termed as a dependent eye. Results: The mean IOP of the dependent eyes increased significantly at 5min after changing from supine to right (16.26(plus or minus)2.73mmHg versus 18.54(plus or minus)2.95mmHg, p<0.01) or left LDP (15.53(plus or minus)2.41mmHg versus 17.53(plus or minus)3.37mmHg, p<0.01); this IOP increase in the dependent eyes persisted at 30min after changing to right (18.47(plus or minus)2.97mmHg, p<0.01) or left LDP (17.79(plus or minus)2.20mmHg, p<0.01). Upon returning to the supine position, IOP of the dependent eyes decreased significantly (16.83(plus or minus)2.67mmHg, p<0.01 for right LDP and 16.47(plus or minus)2.32mmHg, p<0.01 for left). However, this effect of the positional change was not found in the non-dependent eyes (all, p>0.05). Mean IOP in the dependent eye was significantly higher than that in the non-dependent eye at 30min after changing to the right (+0.89(plus or minus) 1.52mmHg) or left LDP (+1.84(plus or minus)2.03mmHg). Conclusion: The postural change from supine to LDP significantly increased IOP of the dependent eyes.
J.Y. Lee. Department of Ophthalmology, Korea University College of Medicine, 126-1 Anam-dong 5-ga, Sungbuk-gu,, .
6.1.3 Factors affecting IOP (Part of: 6 Clinical examination methods > 6.1 Intraocular pressure measurement; factors affecting IOP)