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Abstract #47101 Published in IGR 13-3
Correlation between central corneal thickness and intraocular pressure peak and fluctuation during the water drinking test in glaucoma patients
Furlanetto RL; Facio AC; Hatanaka M; Susanna RClinics 2010; 65: 967-970
OBJECTIVE: To investigate the correlation between central corneal thickness and outflow facility assessed by intraocular pressure peak and fluctuation during the water drinking test. METHODS: Fifty-five newly diagnosed primary open-angle glaucoma patients submitted to central corneal thickness measurements and water drinking test were enrolled in this retrospective study.;. Patients were divided into three groups according to their central corneal thickness. Pearson's Correlation test was performed in the groups with lower and higher pachymetric values.RESULTS: The mean age was 65, 65(plus or minus) 28,28 years; 63,63% were female and 52,72% were caucasian. The mean central corneal thickness was 544, 32(plus or minus) 36, 86 (mu) m, and the mean baseline intraocular pressure was 23,36(plus or minus) 6,26 mmHg. During the water drinking test, the mean intraocular pressure peak and mean intraocular pressure fluctuation were 30, 43(plus or minus) 8,13 mmHg and 31,46(plus or minus) 18,46%, respectively. No relevant correlation was detected between the central corneal thickness and the intraocular pressure peak (r(2) = 0,021) or between the central corneal thickness and the intraocular pressure fluctuation (r(2) = 0,011). Group 1 presented a mean central corneal thickness of 505, 81(plus or minus) 13, 86 im, and Group 3 was 583, 55(plus or minus) 27, 87 \m (p = 0,001). The mean intraocular pressure peak was 31, 05(plus or minus) 9, 05 mmHg and 27, 83(plus or minus) 4, 92 mmHg in Group 1 and in Group 3, respectively (p = 0,193). The difference of intraocular pressure fluctuation was not statistically significant between Group 1 (mean 28, 47(plus or minus) 16,25%) and Group 3 (mean 33,27(plus or minus) 21,27%) (p = 0, 43). CONCLUSION: In our case series, no correlation was found between central corneal thickness and water drinking test results.
R. L. Furlanetto. Glaucoma Service, Department of Ophthalmology, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brazil.
Classification:
6.1.3 Factors affecting IOP (Part of: 6 Clinical examination methods > 6.1 Intraocular pressure measurement; factors affecting IOP)
2.2 Cornea (Part of: 2 Anatomical structures in glaucoma)
6.13 Provocative tests (Part of: 6 Clinical examination methods)
