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Background: To investigate the effect of primary phacoemulsification on intraocular pressure (IOP) in patients with acute primary angle-closure (PAC) and coexisting cataract. Methodology: Sixteen eyes of 14 patients with acute PAC received phacoemulsification and intraocular lens implantation as initial management for medically uncontrolled IOP in a retrospective chart review. The effects on IOP, vision, anterior chamber depth (ACD), and number of antiglaucoma medications were evaluated. Principal Findings: The postoperative IOP was reduced in 16 eyes (100%). The mean (plus or minus) standard deviation preoperative IOP was 48.81(plus or minus)16.83 mm Hg, which decreased postoperatively to 16.46(plus or minus)10.67 mm Hg at 1 day, 9.43(plus or minus)3.03 mm Hg at 1 week, 9.49(plus or minus)2.14 mm Hg at 2 weeks, 10.78(plus or minus)3.56 mm Hg at 1 month, and 10.70(plus or minus)2.80 mm Hg at 3 months (p<0.001). The mean number of antiglaucoma medications decreased from 3.56(plus or minus)1.14 to 0.13(plus or minus)0.34 (p<0.001). The average preoperative ACD was 2.08(plus or minus)0.35 mm, which increased to 3.59(plus or minus)0.33 mm after surgery (p<0.001). Visual acuity (converted into logarithm of the minimum angle of resolution [logMAR]) improved from 1.14(plus or minus)0.71 to 0.73(plus or minus)0.53 (p = 0.001). Conclusions: Primary phacoemulsification plus intraocular lens implantation lowered IOP, reduced the use of antiglaucoma medications, and improved vision in patients with acute PAC. This is a safe and effective method of IOP control and can be considered a first treatment option in managing patients with acute PAC and coexisting cataract.
H. S.-L. Chen. Department of Ophthalmology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan.
9.3.1 Acute primary angle closure glaucoma (pupillary block) (Part of: 9 Clinical forms of glaucomas > 9.3 Primary angle closure glaucomas)
12.12.3 Phacoemulsification (Part of: 12 Surgical treatment > 12.12 Cataract extraction)