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Abstract #47507 Published in IGR 13-4
Corneal Hysteresis and Beta-Zone Parapapillary Atrophy
Hayes DD; Teng CC; De Moraes CG; Tello C; Liebmann JM; Ritch RAmerican Journal of Ophthalmology 2011;
Purpose: To evaluate the relationship between (beta)-zone parapapillary atrophy ((beta)PPA) and corneal hysteresis (CH) in patients with glaucoma. Design: Prospective, cross-sectional study. Methods: Glaucoma patients aged 18 to 90 years with disc photographs within 12 months of the study visit were consecutively enrolled. Exclusion criteria included ocular surgery other than clear corneal phacoemulsification, myopia >6 diopters, contact lens use, and corneal abnormality. CH was measured using the Ocular Response Analyzer (ORA). Disc photographs were evaluated in a masked fashion for (beta)PPA. Results: We enrolled 99 patients (mean age 67.6 years; 45 men, 54 women). Univariate analysis showed no significant difference in CH between eyes with and without (beta)PPA (8.72 (plus or minus) 0.23 vs 8.15 (plus or minus) 0.27 mm Hg, P = .11). There were no differences in corneal resistance factor (CRF) (P = .47), central corneal thickness (CCT) (P = .11), ORA wave score (P = .23), age (P = .23), sex (P = .40), IOP (P = .86), or visual field mean deviation (VFMD) (P = .45). Eyes with (beta)PPA were more myopic (-1.49 (plus or minus) 0.27 vs -0.22 (plus or minus) 0.31 diopters, P = .003). Multivariate analysis showed no significant difference in CH between eyes with and without (beta)PPA (P = .38). Eyes with asymmetric (beta)PPA also showed no significant difference in CH (8.97 (plus or minus) 0.22 vs 9.10 (plus or minus) 0.22 mm Hg, P = .69). Conclusions: We found no significant differences in CH between eyes with and without (beta)PPA or between fellow eyes with asymmetric (beta)PPA. (copyright) 2011 Elsevier Inc. All rights reserved.
R. Ritch. Einhorn Clinical Research Center, New York Eye and Ear Infirmary, New York, New York, . Email: ritchmd@earthlink.net
Classification:
6.1.1 Devices, techniques (Part of: 6 Clinical examination methods > 6.1 Intraocular pressure measurement; factors affecting IOP)
2.14 Optic disc (Part of: 2 Anatomical structures in glaucoma)
6.8.2 Posterior segment (Part of: 6 Clinical examination methods > 6.8 Photography)
