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Abstract #47549 Published in IGR 13-4
Current status of genome research on open-angle glaucoma in Finland
Forsman E; Lemmela S; Puska P; Jarvela IDuodecim; laaketieteellinen aikakauskirja 2011; 127: 1426-1431
Loss of vision and visual impairment due to glaucoma can be prevented or delayed, if the disease is detected at an early stage. The most important risk factors for open-angle glaucoma include age, elevated intraocular pressure, exfoliation of the lens, i.e. exfoliation syndrome, and genetic factors. To date, genetic studies on glaucoma have revealed more than 20 gene loci and three candidate genes, myocilin (MYOC), optineurin (OPTN) and WD repeat domain 36 (WDR36). A mutation in both the MYOC and WDR36 genes has been found in Finnish families. LA: Finnish
E. Forsman. Folkhalsanin Tutkimuskeskus, Geneettisen Epidemiologian Osasto.
Classification:
3.4.2 Gene studies (Part of: 3 Laboratory methods > 3.4 Molecular genetics)