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Background: Conventional risk factors for retinal vein occlusion (RVO) are well established through large epidemiological studies, but triggering factors remain poorly known. Patients and methods: A prospective observational study through a questionnaire was completed between January and October 2009 by patients with RVO and controls. Results: Sixty-one patients, including 42 central retinal vein occlusions (CRVO) and 19 branch vein occlusions (BRVO) as well as 118 controls were included. Of the CRVO patients, 77% discovered visual loss upon awakening in contrast to only 33% of BRVO patients. The comparison between RVO and controls showed a higher proportion in the RVO group for (in order of the highest risk): migraine headache (CRVO, 21 %; BRVO, 47 %; controls, 13 %; p = 0.008), hypertension (CRVO, 52%; BRVO, 63%; controls, 37%; p = 0.012), glaucoma (CRVO, 33%; BRVO, 22%; controls, 16%; p = 0.034), antiplatelet or anticoagulant medication (CRVO, 42%; BRVO, 33%; controls, 26%; p = 0.074), hyperlipidemia, ocular trauma, sudden deafness, or vertigo. The prevalence was similar in both groups for body mass index, history of phlebitis or peptic ulcer, smoking habits, stress, fasting, dehydration, vasodilator intake, and altitude stay. Conclusion: In addition to the already known risk factors, this study underlines certain underlying conditions or circumstances related to the onset of RVO, such as migraine. In CRVO, three-quarters of the patients on average discovered visual loss upon awakening, which may indicate that nocturnal events may play a significant role in the pathogenesis of the occlusion. (copyright) 2011 Elsevier Masson SAS. All rights reserved. LA: French
J. Tilleul. Service d'Ophtalmologie, L'Hopital Intercommunal de Creteil, Universite Paris-XII-Henri-Mondor, 40, avenue de Verdun, 94000 Creteil, France. Email: julien.tilleul@free.fr
9.4.5.5 Other (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders > 9.4.5 Glaucomas associated with disorders of the retina, choroid and vitreous)