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Purpose: We performed a comparative study using Goldmann applanation tonometry (GAT) and dynamic contour tonometry (DCT) to measure intraocular pressure (IOP) in eyes with keratoconus. Methods: IOP was measured in 114 eyes of 75 patients with keratoconus (51 men and 24 women; mean age, 36.1 (plus or minus) 11.2 years) using GAT and DCT in randomized order. Central corneal thickness (CCT), minimal corneal thickness (MCT), and corneal topography were recorded using the Pentacam. Four groups according to Amsler's keratoconus classification were composed and analyzed for significant differences of CCT, MCT, GAT, and DCT results. Results:: Mean CCT in the 114 keratoconus eyes was 481.1 (plus or minus) 46.2 (mu)m (range, 334-601 (mu)m). Mean MCT was 453.3 (plus or minus) 56.3 (mu)m (range, 239-573 (mu)m). Mean IOP measured using GAT was 13.1 (plus or minus) 2.9 mm Hg, whereas mean IOP measured using DCT was 14.8 (plus or minus) 2.6 mm Hg. Neither the results for GAT nor those for DCT showed a significant correlation with CCT (Pearson correlation: P < 0.05). Multifactorial analysis revealed that CCT and MCT, but not GAT and DCT, results were significantly different in corneas of varying curvatures. Conclusions: This study shows that DCT measures IOP higher than GAT in eyes with keratoconus. In keratoconus, both methods seem to be independent of CCT and therefore are equally, but not interchangeably, applicable when monitoring IOP. Further analysis revealed that CCT and MCT are significantly different in corneas of varying Amsler grade. Copyright (copyright) 2011 by Lippincott Williams & Wilkins.
J.D. Unterlauft. University Eye Hospital, University of Wuerzburg, Josef-Schneider-Strasse 11, 97080 Wuerzburg, Germany. Email: j.d.unterlauft@gmx.de
6.1.1 Devices, techniques (Part of: 6 Clinical examination methods > 6.1 Intraocular pressure measurement; factors affecting IOP)
2.2 Cornea (Part of: 2 Anatomical structures in glaucoma)