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Abstract #47797 Published in IGR 13-4
Comparison of optic disc topography in the cases with graves disease and healthy controls
Sen E; Berker D; Elgin U; Tutuncu Y; Ozturk F; Guler SJournal of Glaucoma 2011;
PURPOSE: To compare the optic nerve head topographic parameters of the cases with Graves disease (GD), and the age and sex-matched control group, by using Heidelberg retinal tomography III. MATERIALS AND METHODS: We evaluated both eyes of 65 patients with GD and 54 age and sex-matched controls. For statistical analysis, Mann-Whitney U test and independent sample t test were used. Statistical significance was set as P<0.05. RESULTS: The study group consisted of 22 male (33.8%) and 43 female (66.2%) GD cases with a mean age of 40.3(plus or minus)11.9 years and the control group consisted of 26 male (48.1%) and 28 female (51.9%) healthy controls with a mean age of 36.9(plus or minus)7.6 years. The differences between the age and sexes of the groups were not statistically significant (P=0.07 and P=0.11, respectively). The mean intraocular pressure of the study group was 14.6(plus or minus)2.9 mm Hg (range, 8 to 20 mm Hg), whereas in the control group, it was 13.4(plus or minus)2.1 mm Hg (range, 10 to 19 mm Hg). The difference between the intraocular pressures was statistically significant (P=0.01). The mean retinal nerve fiber layer (RNFL) thickness (0.31(plus or minus)0.08 mm) and the mean RNFL cross-sectional area (1.5 (plus or minus)0.43 mm) of the control group were greater than the mean RNFL thickness (0.25(plus or minus)0.06 mm) and the mean RNFL cross-sectional area (1.30(plus or minus)0.32 mm) of the study group (P=0.02, P=0.03 respectively). CONCLUSIONS: This result suggests that patients with GD may have thinner RNFL than healthy controls.
E. Sen.
Classification:
9.4.15 Glaucoma in relation to systemic disease (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)
2.13 Retina and retinal nerve fibre layer (Part of: 2 Anatomical structures in glaucoma)
6.9.1.1 Confocal Scanning Laser Ophthalmoscopy (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis > 6.9.1 Laser scanning)
