advertisement
Abstract #47805 Published in IGR 13-4
Quantification of retinal nerve fiber layer thickness after unilateral acute primary angle closure in Asian Indian eyes
Mansoori T; Viswanath K; Balakrishna NJournal of Glaucoma 2011;
PURPOSE: To determine retinal nerve fiber layer thickness (RNFLT) using Spectral optical coherence tomography/scanning laser ophthalmoscope (Spectral OCT/SLO) in Asian Indian eyes after single, unilateral attack of acute primary angle closure (APAC). METHODS: Thirty-two patients with unilateral attack of APAC with normal optic disc and normal visual field, unaffected fellow eyes, and 35 age-matched normal control eyes were enrolled for the study. Six weeks after the remission of acute attack, peripapillary average, quadrant, and clock-hour RNFLT were compared between 3 groups using Spectral OCT/SLO. RESULTS: APAC patients had mean IOP of 51.3(plus or minus)13.3 mm Hg (range, 40-74) at the time of presentation with acute attack in the affected eye and 14.9(plus or minus)2.9 mm Hg at 6 weeks after resolution of APAC. Duration of symptoms of acute attack was 35.9(plus or minus)23.8 hours. Significant differences were found between RNFLT in APAC and fellow eyes for most the parameters except for 1, 4, 6, and 7-o'clock-hour sector. Most of the RNFLT parameters showed statistically significant difference between APAC and normal control eyes except for temporal quadrant, 6, 7-o'clock-hour sectors. Statistically significant differences were found between RNFLT in unaffected fellow and normal control eyes for most of the parameters except for 6, 7, 11 o'clock-hour sectors. CONCLUSIONS: RNFLT was found to be significantly thinner in APAC and unaffected fellow eyes when compared with normal age-matched controls. Hence, patients with APAC should be monitored carefully to determine its long-term effects on optic disc, RNFLT, and visual fields. Longitudinal studies can determine whether the RNFLT measurements remained stable or showed progression in these patients.
T. Mansoori.
Classification:
9.3.1 Acute primary angle closure glaucoma (pupillary block) (Part of: 9 Clinical forms of glaucomas > 9.3 Primary angle closure glaucomas)
2.13 Retina and retinal nerve fibre layer (Part of: 2 Anatomical structures in glaucoma)
6.9.1.1 Confocal Scanning Laser Ophthalmoscopy (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis > 6.9.1 Laser scanning)
6.9.2.2 Posterior (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis > 6.9.2 Optical coherence tomography)
