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Abstract #47933 Published in IGR 13-4

In vivo measurement of regional variation in anterior scleral resistance to Schiotz indentation

Patel H; Gilmartin B; Cubbidge RP; Logan NS
Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians 2011; 31: 437-443

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Recent studies indicate that ocular and scleral rigidity is pertinent to our understanding of glaucoma, age related macular degeneration and the development and pathogenesis of myopia. The principal method of measuring ocular rigidity is by extrapolation of data from corneal indentation tonometry (K(o) ) using Friedenwald's transformation algorithms. Using scleral indentation (Schiotz tonometry) we assess whether regional variations in resistance to indentation occur in vivo across the human anterior globe directly, with reference to the deflection of Schiotz scale readings. Data were collected from both eyes of 26 normal young adult subjects with a range of refractive error (mean spherical equivalent(plus or minus)S.D. of -1.77D(plus or minus)3.28D, range -10.56 to +4.38D). Schiotz tonometry (5.5g & 7.5g) was performed on the cornea and four scleral quadrants; supero-temporal (ST) and -nasal (SN), infero-temporal (IT) and -nasal (IN) approximately 8mm posterior to the limbus. Values of K(o) (mm(3) )(-1) were consistent with those previously reported (mean 0.0101(plus or minus)0.0082, range 0.0019-0.0304). In regards to the sclera, significant differences (p<0.001) were found across quadrants with indentation readings for both loads between means for the cornea and ST; ST and SN; ST and IT, ST and IN. Mean ((plus or minus)S.D.) scale readings for 5.5g were: cornea 5.93(plus or minus)1.14, ST 8.05(plus or minus)1.58, IT 7.03(plus or minus)1.86, SN 6.25(plus or minus)1.10, IN 6.02(plus or minus)1.49; and 7.5g: cornea 9.26(plus or minus)1.27, ST 11.56(plus or minus)1.65, IT 10.31(plus or minus)1.74, SN 9.91(plus or minus) 1.20, IN 9.50(plus or minus)1.56. Significant regional variation was found in the resistance of the anterior sclera to indentation produced by the Schiotz tonometer. Ophthalmic & Physiological Optics (copyright) 2011 The College of Optometrists.

H. Patel. Ophthalmic Research Group, School of Life & Health Sciences, Aston University, Birmingham, UK. Email: h.d.patel1@aston.ac.uk

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Classification:

6.1.1 Devices, techniques (Part of: 6 Clinical examination methods > 6.1 Intraocular pressure measurement; factors affecting IOP)
2.3 Sclera (Part of: 2 Anatomical structures in glaucoma)

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