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(15)

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Abstract #48027 Published in IGR 13-4

Heart block following topical latanoprost treatment

De Smit E; Theodorou M; Hildebrand GD; Bloom P
British Medical Journal (Clinical Research Edition) Case Reports 2011;

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The authors report a case of second degree heart block associated with topical latanoprost treatment. The authors discuss the possibility of a causative effect as the cessation of this treatment resulted in improvement of the arrhythmia. The authors highlight previous reports and research in humans and animals which demonstrate an association of arrhythmias with prostaglandin analogues. This report draws attention to the possibility that an extremely commonly prescribed topical drug may trigger arrhythmias in susceptible individuals. It is important that prescribers are aware of this possible side-effect. Copyright 2011 BMJ Publishing Group. All rights reserved.

E. De Smit. Eye Unit, Croydon University Hospital, Croydon, United Kingdom. Email: desmitel@doctors.org.uk

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Classification:

11.4 Prostaglandins (Part of: 11 Medical treatment)
9.4.15 Glaucoma in relation to systemic disease (Part of: 9 Clinical forms of glaucomas > 9.4 Glaucomas associated with other ocular and systemic disorders)

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