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Abstract #48548 Published in IGR 14-1
Comparison of newly diagnosed ocular hypertension and open-angle glaucoma: ocular variables, risk factors, and disease severity
Buys YM; Harasymowycz P; Gaspo R; Kwok K; Hutnik CM; Blondeau P; Birt CM; Piemontesi RL; Gould LF; Lesk MR; Ahmed IKJournal of Ophthalmology 2012; 2012: 757106
PURPOSE: To describe the distribution of ocular variables, risk factors, and disease severity in newly diagnosed ocular hypertension (OH) or open-angle glaucoma (OAG). METHODS: Eligible subjects underwent a complete history and examination. Adjusted odds ratios (ORs) and 95% confidence intervals (CIs) obtained from multiple logistic regression models were used to compare OAG to OH and advanced to early/moderate OAG. RESULTS: 405 subjects were enrolled: 292 (72.1%) with OAG and 113 (27.9%) with OH. 51.7% had early, 27.1% moderate, and 20.9% advanced OAG. The OR for OAG versus OH was 8.19 (P < 0.0001) for disc notch, 5.36 (P < 0.0001) for abnormal visual field, 1.45 (P = 0.001) for worsening mean deviation, 1.91 (P < 0.0001) for increased cupping, 1.03 for increased age (P = 0.030), and 0.36 (P = 0.010) for smoking. CONCLUSIONS: Increased age was a risk for OAG, and smoking decreased the risk of OAG compared to OH. Almost half of the OAG subjects had moderate/advanced disease at diagnosis.
Department of Ophthalmology, University of Toronto, 399 Bathurst Street, EW 6-405, Toronto, ON, M5T 2S8, Canada.
Full articleClassification:
9.2.1 Ocular hypertension (Part of: 9 Clinical forms of glaucomas > 9.2 Primary open angle glaucomas)
2.14 Optic disc (Part of: 2 Anatomical structures in glaucoma)
6.6.1 Conventional manual (Part of: 6 Clinical examination methods > 6.6 Visual field examination and other visual function tests)