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Abstract #48806 Published in IGR 14-1

Anterior chamber depth and its associations with ocular and general parameters in adults

Jonas JB; Nangia V; Gupta R; Khare A; Sinha A; Agarwal S; Bhate K
Clinical and Experimental Ophthalmology 2012; 40: 550-556


BACKGROUND: To investigate the normative data of anterior chamber depth and its associations in adults in rural Central India. DESIGN: Population-based study PARTICIPANTS: The Central India Eye and Medical Study included 4711 subjects aged 30+ years (response rate, 80.1%). METHODS: The subjects underwent an ophthalmologic examination including measurement of the anterior chamber depth by sonography. MAIN OUTCOME MEASURE: Anterior chamber depth RESULTS: Mean anterior chamber depth (ACD) was 3.22 ± 0.34 mm. In multivariate analysis, a shallow chamber depth was significantly associated with higher age (P < 0.001), female gender (P < 0.001), shorter body stature (P= 0.003), hyperopic refractive error (P < 0.001), higher lens thickness (P < 0.001), and shorter axial length (P < 0.001). CONCLUSIONS: In the rural Central Indian population, a shallow anterior chamber was associated with higher age, female gender, short body stature, hyperopia, thick lens, and shorter axial length. Compared with population-based data from East Asia (China), the anterior chamber was markedly deeper in India. The data may be helpful to explain anatomic relationships of the anterior segment of the eye, to elucidate risk factors of angle-closure glaucoma, and to explain ethnic differences in the prevalence of angle-closure glaucoma.

Suraj Eye Institute, Nagpur, Maharashtra, India Department of Ophthalmology, Medical Faculty Mannheim of the Ruprecht-Karls-University Heidelberg, Mannheim, Germany.

Full article

Classification:

1.1 Epidemiology (Part of: 1 General aspects)
2.4 Anterior chamber angle (Part of: 2 Anatomical structures in glaucoma)
9.3.5 Primary angle closure (Part of: 9 Clinical forms of glaucomas > 9.3 Primary angle closure glaucomas)



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