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Abstract #50395 Published in IGR 14-2
Ocular rigidity: bio-mechanical role, in vivo measurements and clinical significance
Detorakis ET; Pallikaris IGClinical and Experimental Ophthalmology 2013; 41: 73-81
Ocular rigidity (OR) refers to the relationship between pressure and volume changes in the eyeball and is associated with the bio-mechanical behaviour of the eye. Since the description of the differential tonometry method for the calculation of an OR coefficient by Friedenwald, several other methodologies have been proposed to measure OR for an individual eye, including the anterior chamber manometry, axial length (AL) changes, measurement of pulse amplitude and fundus pulse, ultrasound elastography and evaluation of corneal hysteresis. However, most of these methodologies suffer from deficiencies, such as invasive nature, poor accuracy or reproducibility or technical complexity, which compromise their wide-spread application in clinical practice. Nevertheless, it is possible that OR affects the pathogenesis and clinical course of a variety of ocular conditions, including glaucoma, age-related macular degeneration, presbyopia and corneal changes following refractive surgery. The accuracy of IOP measurements by many tonometers, including the gold-standard Goldmann applanation tonometry, is also affected by OR. The importance of incorporating OR in clinical decision making justifies further research towards the development of non-invasive and easy-to-use methodologies for the accurate measurement of OR in the every-day practice. © 2012 The Authors. Clinical and Experimental Ophthalmology © 2012 Royal Australian and New Zealand College of Ophthalmologists.
Department of Ophthalmology, University Hospital of Heraklion, Crete, Greece Institute of Vision and Optics (IVO), Heraklion, Crete, Greece.
Full articleClassification:
6.2 Tonography, aqueous flow measurement (see also 2.6) (Part of: 6 Clinical examination methods)
2.2 Cornea (Part of: 2 Anatomical structures in glaucoma)
