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Abstract #50963 Published in IGR 14-3
Prevalence and predictors of depression among participants with glaucoma in a nationally representative population sample
Wang SY; Singh K; Lin SCAmerican Journal of Ophthalmology 2012; 154: 436-444.e2
PURPOSE: To investigate the prevalence of and risk factors for depression among participants with glaucoma and the predictive value of glaucoma for depression. DESIGN: Cross-sectional study. METHODS: This study included 6760 participants in the National Health and Nutrition Examination Survey (NHANES) between 2005 and 2008, aged ≥40 years, who reported a presence or absence of glaucoma. Demographic and disease-related information was obtained by interview. Self-reported measures of vision were ascertained via items from the Visual Function Questionnaire (VFQ-25). Participants underwent visual acuity examination, fundus photography, and visual field testing with screening frequency-doubling technology (FDT N-30-5). The main outcome was presence of depression, as determined by a score ≥10 on the Patient Health Questionnaire-9 (PHQ-9). RESULTS: Prevalence of depression among participants with and without glaucoma was 10.9% (SEM 2.2%) and 6.9% (SEM 0.62%), respectively. While the presence of glaucoma was significantly associated with depression after adjustment for demographic factors (OR 1.80, 95% CI 1.16-2.79), this association was not significant after adjustment for self-reported general health condition (OR 1.35, 95% CI 0.822-2.23). Among participants with glaucoma, objective measures of glaucoma severity were not significant predictors for depression. However, several self-reported measures of visual function were significantly associated with depression. CONCLUSIONS: Glaucoma is a significant predictor of depression after adjustment for demographic factors and multiple comorbidities, but not after adjustment for self-reported general health condition. Among participants with glaucoma, self-reported measures of vision were significant risk factors for depression, whereas objective measures of vision were not.
Department of Ophthalmology, University of California, San Francisco, San Francisco, California, USA.
Full articleClassification:
1.4 Quality of life (Part of: 1 General aspects)
