advertisement
Abstract #51320 Published in IGR 14-3
Glaucoma risk assessment using a non-linear multivariable regression method
Kourkoutas D; Karanasiou IS; Tsekouras GJ; Moshos M; Iliakis E; Georgopoulos GComputer Methods and Programs in Biomedicine 2012; 108: 1149-1159
The present research investigates the relationship between the central corneal thickness (CCT), Heidelberg Retina Tomograph II (HRTII) structural measurements and intraocular pressure (IOP) using an innovative non-linear multivariable regression method in order to define the risk factors in future glaucoma development and patient management. The method is implemented to data from ninety-three open angle glaucoma eyes. The results show that in established glaucoma, CCT is significantly associated with HRTII structural measurements (maximum contour depression, cup volume inferotemporally) and IOP. They are also compared to those obtained from the application of standard linear regression methods, improving the coefficient determination R(2) by 35%, exhibiting thus the performance of the proposed methodology.
Department of Ophthalmology, 401 Hellenic Army General Hospital, 1 P. Kanellopoulou Avenue, 11525 Athens, Greece; Department of Ophthalmology, Glaucoma Unit, Medical School, University of Athens, Micras Asias 75, Goudi, Athens, Greece. Electronic address: d_kourkoutas@hotmail.gr.
Full articleClassification:
6.9.1.1 Confocal Scanning Laser Ophthalmoscopy (Part of: 6 Clinical examination methods > 6.9 Computerized image analysis > 6.9.1 Laser scanning)
2.2 Cornea (Part of: 2 Anatomical structures in glaucoma)
