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PURPOSE: To report a case of primary infantile glaucoma occurring in only one of two identical twins. METHODS: Case reports. RESULTS: Clinical features of bilateral primary infantile glaucoma in one of the two twins at age 16 months are described. Polymorphic DNA markers were used to establish identical twinship. CONCLUSION: Our finding suggests that nongenetic factors must be considered in determining the origin of primary infantile glaucoma.
Dr. H.D. Jampel, Maumenee B-110, Wilmer Eye Institute, Johns Hopkins Hospital, 600 N Wolfe St, Baltimore, MD 21287; United States
1.2 Population genetics (Part of: 1 General aspects)