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Abstract #51717 Published in IGR 14-4
High versus low density multifocal pupillographic objective perimetry in glaucoma
Maddess T; Essex RW; Kolic M; James ACClinical and Experimental Ophthalmology 2013; 41: 140-147
BACKGROUND: We compared multifocal pupillographic objective perimetry (mfPOP) using 24 and 44 regions per visual field. DESIGN: Experimental design in a university setting. PARTICIPANTS: 27 normal control and 36 age-matched glaucoma patients. METHODS: The four test variants differed in the mean interval between stimuli: 4, 1 or 0.25 s; and the number of visual field regions tested within the central 60 degrees: 24 or 44. All subjects had their diagnostic status confirmed by optical coherence tomography, two forms of perimetry, and slit lamp bio-microscopy. Both eyes were measured concurrently in 2.73 ± 0.45 min/eye (mean ± SD), and tests were repeated about 2 weeks apart. MAIN OUTCOME MEASURES: The main outcome measures were: 1) mean change in light sensitivity due glaucoma; 2) areas under Receiver Operator Characteristic plots for detecting glaucoma RESULTS: For all four variants consensual responses, female gender and age produced small but significant sensitivity differences, and sensitivity declined with age by ≤ -0.27 dB/decade (all p < 0.0003). The best diagnostic accuracy (area under curve 93.2 ± 3.89%) was produced by the 1 presentation/s 44-region protocol. Across the 4 protocols the effect of repeat testing was small (all methods ≤ 0.15 dB). CONCLUSIONS: Presentation rate had little effect but increasing the tested density from 24 to 44 regions/field improved diagnostic power. Given that mfPOP also provides information on response delay and afferent versus efferent defects at every visual field region it may be a useful adjunct to perimetry.
The ARC Vision Centre, John Curtin School of Medical Research, Australian National University, Canberra, ACT, Australia.
Full articleClassification:
6.6.3 Special methods (e.g. color, contrast, SWAP etc.) (Part of: 6 Clinical examination methods > 6.6 Visual field examination and other visual function tests)
